Specialized hip and knee care, close to home.
Whether you need a clearer diagnosis, an injection, or joint replacement, Dr. Rhett MacNeille starts with the least invasive option likely to help. When surgery is appropriate, he combines CT-based Mako planning with muscle-sparing approaches and an evidence-based recovery plan tailored to you.
Adult Reconstruction Fellowship, Hedley Orthopaedic Institute
Training · Board-Certified (ABOS) · Professional Affiliations
Specialized care for one thing: your hips and knees.
Dr. MacNeille is a board-certified, fellowship-trained total joint replacement surgeon at the Orthopaedic Institute of Southern Illinois, focused exclusively on disorders of the hip and knee — from arthritis care and injections to robotic joint replacement and complex revisions.
- Medical Degree — Penn State College of Medicine
- Orthopaedic Residency — Loma Linda University Medical Center
- Adult Reconstruction Fellowship — Hedley Orthopaedic Institute of the West
- Published researcher in joint replacement · Licensed in IL, CA & AZ
From diagnosis to full recovery
Every treatment ladder starts with an accurate diagnosis and every reasonable non-surgical option — surgery is the last rung, not the first.
Total Knee Replacement
Mako robotic-assisted, through a quadriceps-sparing midvastus approach, personalized for a natural, kinematic knee.
Knee care
Total Hip Replacement
Mako robotic accuracy with a minimally invasive direct superior approach — often with no hip precautions after surgery.
Hip care
Partial Knee Replacement
When only one compartment is worn, replacing just that part preserves healthy bone and ligaments for a faster recovery.
Learn more
Injections & Non-Operative Care
X-ray, CT & MRI diagnostics, cortisone and gel injections, PRP, bracing, knee sleeves, and physical therapy referral.
How they workAlso offering revision hip & knee replacement for joints replaced years ago that have worn or loosened.
Precision on the inside. A gentler recovery on the outside.
A plan built from your CT scan
Every robotic joint replacement starts with a 3D model of your anatomy. The Mako robotic arm helps execute that plan within a millimeter — for accurate alignment, balanced ligaments, and a joint that feels natural.
Protecting what powers recovery
Quadriceps-sparing midvastus approach for knees. Direct superior approach for hips — IT band untouched, key stabilizers preserved, and for most patients, no hip precautions.
Home the same day
Multimodal pain control, aspirin-based blood clot prevention, and therapy that starts right away. Most surgery-center patients walk within hours and sleep in their own bed that night.
See the techniques and recovery milestones
Watch patients up and walking within hours of surgery — and see how Mako robotics plans a joint replacement from a CT scan.
Recovery examples feature patients of Dr. Lige Kaplan — Dr. MacNeille's fellowship director and mentor — treated with the same minimally invasive approaches. Mako explainers and patient stories come from Stryker and partner channels. Local patient stories will be added with permission.
Recovery videos courtesy of Dr. Lige Kaplan — Dr. MacNeille's fellowship director and mentor — whose patients underwent the same minimally invasive techniques Dr. MacNeille uses today. We'll be adding our own patient videos over time.
Understand your joints
Plain-language articles written from the peer-reviewed literature — with citations — so you can make informed decisions.
Robotic-Assisted Total Knee Replacement (Mako)
What the robot actually does, and what studies show about pain, opioid use, and early recovery.
Read article
The Direct Superior Approach to Hip Replacement
A muscle-sparing approach with registry dislocation rates of 0.3% — and often no hip precautions.
Read article
Same-Day Joint Replacement
Randomized trials show outpatient joint replacement is safe for well-selected patients. Here's how it works.
Read articleServing Southern Illinois and the surrounding region
Dr. MacNeille welcomes patients seeking total hip replacement, total knee replacement, and non-operative hip and knee care from Carbondale, Herrin, Marion, and Mt. Vernon — and from communities across the entire region, from Effingham to Metropolis, the St. Louis Metro East, Fairfield, Paducah (KY), and Cape Girardeau (MO).
Carbondale · Herrin · Marion · Mt. Vernon · Murphysboro · Carterville · Du Quoin · Benton · West Frankfort · Harrisburg · Anna · Centralia · Salem · Effingham · Metropolis · Belleville · Edwardsville · St. Louis · Cape Girardeau · Paducah · Evansville
Common questions
Do I need surgery to become a patient?
No. An appointment begins with understanding the problem and discussing reasonable options. Many patients start with non-surgical care — activity changes, therapy, bracing, or injections.
Does the Mako robot perform the surgery?
No. Dr. MacNeille performs the operation. The Mako system helps him create a CT-based plan before surgery and guides the robotic arm within that plan during surgery — it never operates on its own.
Will I go home the day of surgery?
Same-day discharge may be appropriate for eligible patients treated at the outpatient surgery center. Your health, procedure, support at home, and surgical setting all shape the plan — it is decided together, before surgery.
Do I need a referral?
Referral requirements vary by insurance plan. Call 618-998-9998 and the scheduling team will help you confirm what your plan requires.
Ready to take the first step?
Request an appointment and our scheduling team will contact you within 1–2 business days. Every plan starts with listening — and every option, surgical or not, on the table.
Request a Visit