Rhett MacNeille, MD
Board-certified, fellowship-trained total joint replacement surgeon — hips and knees, exclusively.

Training & background
Rhett MacNeille, MD is a board-certified, fellowship-trained total joint replacement surgeon specializing in advanced hip and knee procedures at the Orthopaedic Institute of Southern Illinois. He earned his medical degree at Penn State College of Medicine, completed his orthopaedic surgery residency at Loma Linda University Medical Center, and completed fellowship training in adult reconstruction at the Hedley Orthopaedic Institute of the West. He is certified by the American Board of Orthopaedic Surgery.
Dr. MacNeille has published research on joint replacement and is licensed in Illinois, California, and Arizona. His practice focuses on non-operative treatment of hip and knee pain, minimally invasive robotic assisted total knee and hip replacement, and revision total knee and hip replacement.
- Mako robotic-assisted hip and knee replacement
- Quadriceps-sparing midvastus approach for knees; direct superior approach for hips
- Same-day discharge for most surgery-center patients
- Evidence-based protocols — aspirin clot prevention, multimodal pain control, quiet knee recovery

A consistent team, every case
Joint replacement is a team sport. Dr. MacNeille operates with a dedicated surgical team. The same experienced hands, the same high standards, every single case.
- Dedicated joint replacement surgical team
- Consistent meticulous technique
- Consistent outcomes
Proud to call Southern Illinois home
Dr. MacNeille lives in Southern Illinois with his wife and three children. Outside of medicine, he enjoys boating, hiking, playing piano, and being involved in his church community.

Meet Dr. MacNeille in person
Every plan starts with listening. Request an appointment and our team will contact you within 1–2 business days.
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